Given full-body midday non-burning sun exposure humans create and absorb 10,000 or more IU cholecalciferol.Only when 25(OH)D levels are at/above 125nmol/l(50ng/ml) does vit d work most effectively as an anti inflammatory agent. The regulation of the production of the active hormonal form, Calcitriol is improved when magnesium levels are adequate and omega 3 DHA is available. Therefore to see the full benefit of improved vitamin D3 status we also have to ensure the full RDA for magnesium is in the diet and the omega 3 omega 6 ratio is at/beloe 1 n3 <> 4n6.It is extremely sad to see health professionals continuing to put patients health in jeopardy by failing to meet the natural Vitamin D3, Omega 3 and magnesium levels that human DNA evolved with. Fortunately effective strength D3 is available and you should be able to find a years supply of 5000iu/drops for less than £5. CityAssays Birmingham NHS path lab do 25(OH)D tests by post for £25 and magnesium chelates, and omega 3 DHA concentrated capsules are also readily available. We can all monitor our own pain levels, infections, and progress and record the results. The starting position should be that the levels naturally attained and maintained while living naked outdoor lives eating those food readily available to evolving humans is safe. (Otherwise we wouldn't have survived the evolutionary process) Therefore adopting the vit d/magnesium/omega 3 ratio closest to that at which human DNA evolved should be the priority.Would you trust a garage that suggested you kept your car pressures/fluid levels about a quarter of the manufacturers specifications and advised the wrong grade/type of fuel?